Publikationen 2021

Dezember

The Molecular Biodiversity of Protein Targeting and Protein Transport Related to the Endoplasmic Reticulum. Tirincsi A, Sicking M, Hadzibeganovic D, Haßdenteufel S, Lang S. Int J Mol Sci. 2021 Dec 23;23(1):143. doi: 10.3390/ijms23010143. PMID: 35008565; PMCID: PMC8745461.

November

Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy. Bertero E, Nickel A, Kohlhaas M, Hohl M, Sequeira V, Brune C, Schwemmlein J, Abeßer M, Schuh K, Kutschka I, Carlein C, Münker K, Atighetchi S, Müller A, Kazakov A, Kappl R, von der Malsburg K, van der Laan M, Schiuma AF, Böhm M, Laufs U, Hoth M, Rehling P, Kuhn M, Dudek J, von der Malsburg A, Prates Roma L, Maack C.Circulation 2021 Nov 23;144(21):1694-1713. doi: 10.1161/CIRCULATIONAHA.121.053755. Epub 2021 Oct 14. PMID: 34648376.

Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells. Pick T, Beck A, Gamayun I, Schwarz Y, Schirra C, Jung M, Krause E, Niemeyer BA, Zimmermann R, Lang S, Anken EV, Cavalié ACell Calcium. 2021 Nov;99:102473. doi: 10.1016/j.ceca.2021.102473. Epub 2021 Sep 13. PMID: 34560367.

Oktober

Prolactin-sensitive olfactory sensory neurons regulate male preference in female mice by modulating responses to chemosensory cues. Aoki M, Gamayun I, Wyatt A, Grünewald R, Simon-Thomas M, Philipp SE, Hummel O, Wagenpfeil S, Kattler K, Gasparoni G, Walter J, Qiao S, Grattan DR, Boehm U. Sci Adv. 2021 Oct 8;7(41):eabg4074. doi: 10.1126/sciadv.abg4074. Epub 2021 Oct 8. PMID: 34623921; PMCID: PMC8500514.

September

Lights, Camera, Interaction: Studying Protein-Protein Interactions of the ER Protein Translocase in Living Cells. Sicking M, Jung M, Lang SInt J Mol Sci. 2021 Sep 26;22(19):10358. doi: 10.3390/ijms221910358. PMID: 34638699; PMCID: PMC8508666.

August

Activity of the yeast vacuolar TRP channel TRPY1 is inhibited by Ca 2+-calmodulin binding. Amini M, Chang Y, Wissenbach U, Flockerzi V, Schlenstedt G, Beck A. J Biol Chem. 2021 Oct;297(4):101126. doi: 10.1016/j.jbc.2021.101126. Epub 2021 Aug 28. PMID: 34461097; PMCID: PMC8449268.

Cavβ3 Regulates Ca 2+ Signaling and Insulin Expression in Pancreatic β-Cells in a Cell-Autonomous Manner. Fecher-Trost C, Sen Q, Martus D, Beck A, Philipp SE, Flockerzi V, Belkacemi A. Diabetes. 2021 Nov;70(11):2532-2544. doi: 10.2337/db21-0078. Epub 2021 Aug 23. PMID: 34426509.

Auxiliary Subunits Regulate the Dendritic Turnover of AMPA Receptors in Mouse Hippocampal Neurons. Harb A, Vogel N, Shaib A, Becherer U, Bruns D, Mohrmann R. Front Mol Neurosci. 2021 Aug 23;14:728498. doi: 10.3389/fnmol.2021.728498. PMID: 34497491; PMCID: PMC8419334.

Juli

Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1. Väth K, Mattes C, Reinhard J, Covino R, Stumpf H, Hummer G, Ernst R. J Cell Biol. 2021 Aug 2;220(8):e202011078. doi: 10.1083/jcb.202011078. Epub 2021 Jul 1. PMID: 34196665.

A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity. Kaschek L, Zöphel S, Knörck A, Hoth MSemin Cell Dev Biol. 2021 Jul;115:10-18. doi: 10.1016/j.semcdb.2020.12.002. Epub 2021 Jan 6. PMID: 33358089.

Juni

From Physiology to Pathology of Cortico-Thalamo-Cortical Oscillations: Astroglia as a Target for Further Research. Gobbo D, Scheller A, Kirchhoff F. Front Neurol. 2021 Jun 9;12:661408. doi: 10.3389/fneur.2021.661408. PMID: 34177766; PMCID: PMC8219957.

Mai

Time-resolved proteomics profiling of the ciliary Hedgehog response. May EA, Kalocsay M, D'Auriac IG, Schuster PS, Gygi SP, Nachury MV, Mick DU. J Cell Biol. 2021 May 3;220(5):e202007207. doi: 10.1083/jcb.202007207. PMID: 33856408.

April

Complexity and Specificity of Sec61-Channelopathies: Human Diseases Affecting Gating of the Sec61 Complex. Sicking M, Lang S, Bochen F, Roos A, Drenth JPH, Zakaria M, Zimmermann R, Linxweiler M. Cells. 2021 Apr 27;10(5):1036. doi: 10.3390/cells10051036. PMID: 33925740.

März

A central mechanism of analgesia in mice and humans lacking the sodium channel NaV1.7. Neuron. MacDonald DI, Sikandar S, Weiss J, Pyrski M, Luiz AP, Millet Q, Emery EC, Mancini F, Iannetti GD, Alles SRA, Arcangeletti M, Zhao J, Cox JJ, Brownstone RM, Zufall F, Wood JN. J.neuron 2021 Mar 12:S0896-6273(21)00160-4. doi: 10.1016. Epub ahead of print. PMID: 33823138.

Biogenesis of large dense core vesicles in mouse chromaffin cells. Dembla E, Becherer U. Traffic. 2021 Mar; 22(3):78-93. doi: 10.1111/tra.12783. Epub 2021 Jan 12. PMID: 33369005. 

Signal transduction in primary cilia - analyzing and manipulating GPCR and second messenger signaling. Wachten D, Mick DU. Pharmacol Ther. 2021 Mar 18; 224:107836. doi: 10.1016/j.pharmthera.2021.107836. Epub ahead of print. PMID: 33744260.

Februar

The TRPV2 channel mediates Ca2+ influx and the Δ9-THC-dependent decrease in osmotic fragility in red blood cells. Belkacemi A, Trost CF, Tinschert R, Flormann D, Malihpour M, Wagner C, Meyer MR, Beck A, Flockerzi V. Haematologica. 2021 Feb 18. doi: 10.3324/haematol.2020.274951. Epub ahead of print. PMID: 33596644.

Januar

Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility. Reuter M, Kooshapur H, Suda JG, Gaussmann S, Neuhaus A, Brühl L, Bharti P, Jung M, Schliebs W, Sattler M, Erdmann R. J. Mol Biol. 2021 Mar 5;433(5):166765. doi: 10.1016/j.jmb.2020.166765. Epub 2021 Jan 21. PMID: 33484719. 

The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor. Eesmaa A, Yu LY, Göös H, Nõges K, Kovaleva V, Hellman M, Zimmermann R, Jung M, Permi P, Varjosalo M, Lindholm P, Saarma M. J Biol Chem. 2021 Jan 15;296:100295. doi: 10.1016/j.jbc.2021.100295. Epub ahead of print. PMID: 33460650; PMCID: PMC7949057.