Publikationen 2021


Time-resolved proteomics profiling of the ciliary Hedgehog response. May EA, Kalocsay M, D'Auriac IG, Schuster PS, Gygi SP, Nachury MV, Mick DU. J Cell Biol. 2021 May 3;220(5):e202007207. doi: 10.1083/jcb.202007207. PMID: 33856408.


Complexity and Specificity of Sec61-Channelopathies: Human Diseases Affecting Gating of the Sec61 Complex. Sicking M, Lang S, Bochen F, Roos A, Drenth JPH, Zakaria M, Zimmermann R, Linxweiler M. Cells. 2021 Apr 27;10(5):1036. doi: 10.3390/cells10051036. PMID: 33925740.


A central mechanism of analgesia in mice and humans lacking the sodium channel NaV1.7. Neuron. MacDonald DI, Sikandar S, Weiss J, Pyrski M, Luiz AP, Millet Q, Emery EC, Mancini F, Iannetti GD, Alles SRA, Arcangeletti M, Zhao J, Cox JJ, Brownstone RM, Zufall F, Wood JN. J.neuron 2021 Mar 12:S0896-6273(21)00160-4. doi: 10.1016. Epub ahead of print. PMID: 33823138.

Biogenesis of large dense core vesicles in mouse chromaffin cells. Dembla E, Becherer U. Traffic. 2021 Mar; 22(3):78-93. doi: 10.1111/tra.12783. Epub 2021 Jan 12. PMID: 33369005. 

Signal transduction in primary cilia - analyzing and manipulating GPCR and second messenger signaling. Wachten D, Mick DU. Pharmacol Ther. 2021 Mar 18; 224:107836. doi: 10.1016/j.pharmthera.2021.107836. Epub ahead of print. PMID: 33744260.


The TRPV2 channel mediates Ca2+ influx and the Δ9-THC-dependent decrease in osmotic fragility in red blood cells. Belkacemi A, Trost CF, Tinschert R, Flormann D, Malihpour M, Wagner C, Meyer MR, Beck A, Flockerzi V. Haematologica. 2021 Feb 18. doi: 10.3324/haematol.2020.274951. Epub ahead of print. PMID: 33596644.


Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility. Reuter M, Kooshapur H, Suda JG, Gaussmann S, Neuhaus A, Brühl L, Bharti P, Jung M, Schliebs W, Sattler M, Erdmann R. J. Mol Biol. 2021 Mar 5;433(5):166765. doi: 10.1016/j.jmb.2020.166765. Epub 2021 Jan 21. PMID: 33484719. 

The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor. Eesmaa A, Yu LY, Göös H, Nõges K, Kovaleva V, Hellman M, Zimmermann R, Jung M, Permi P, Varjosalo M, Lindholm P, Saarma M. J Biol Chem. 2021 Jan 15;296:100295. doi: 10.1016/j.jbc.2021.100295. Epub ahead of print. PMID: 33460650; PMCID: PMC7949057.