Publications 2019

November

The Mgr2 subunit of the TIM23 complex regulates membrane insertion of marginal stop-transfer signals in the mitochondrial inner membrane. Lee S, Lee H, Yoo S, Ieva R, van der Laan M, von Heijne G, Kim H. FEBS Lett. 2019 Nov 25. doi: 10.1002/1873-3468.13692.

Oktober

Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour. Bufe B, Teuchert Y, Schmid A, Pyrski M, Pérez-Gómez A, Eisenbeis J, Timm T, Ishii T, Lochnit G, Bischoff M, Mombaerts P, Leinders-Zufall T, Zufall F. Nat Commun. 2019 Oct 25;10(1):4889. doi: 10.1038/s41467-019-12842-x.

September

Calibrating Evanescent-Wave Penetration Depths for Biological TIRF Microscopy. Oheim M, Salomon A, Weissman A, Brunstein M, Becherer U. Biophys J. 2019 Sep 3;117(5):795-809. doi: 10.1016/j.bpj.2019.07.048. 

TRPC channels regulate Ca²⁺-signaling and short-term plasticity of fast glutamatergic synapses. Schwarz Y, Oleinikov K, Schindeldecker B, Wyatt A, Weißgerber P, Flockerzi V, Boehm U, Freichel M, Bruns D. PLoS Biol. 2019 Sep 19;17(9):e3000445. doi: 10.1371/journal.pbio.3000445.

July

Establishing and regulating the composition of cilia for signal transduction. Nachury MV, Mick DU. Nat Rev Mol Cell Biol. 2019 Jul;20(7):389-405. doi: 10.1038/s41580-019-0116-4. Review.

ER import of small human presecretory proteins: components and mechanisms. Haßdenteufel S, Nguyen D, Helms, Lang S, Zimmermann R. FEBS Lett. 2019 Jul 19. doi: 10.1002/1873-3468.13542.

Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Faelber K, Dietrich L, Noel JK, Wollweber F, Pfitzner AK, Mühleip A, Sánchez R, Kudryashev M, Chiaruttini N, Lilie H, Schlegel J, Rosenbaum E, Hessenberger M, Matthaeus C, Kunz S, von der Malsburg A, Noé F, Roux A, van der Laan M, Kühlbrandt W, Daumke O. Nature. 2019 Jul;571(7765):429-433. doi: 10.1038/s41586-019-1372-3. Epub 2019 Jul 10.

June

Alternative UNC13D Promoter Encodes a Functional Munc13-4 Isoform Predominantly Expressed in Lymphocytes and Platelets. Galgano D, Soheili T, Voss M, Torralba-Raga L, Tesi B, Cichocki F, Andre I, Rettig J, Cavazzana M, Bryceson. Front Immunol. 2020 Jun 9;11:1154. 

Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme. Boos F, Krämer L, Groh C, Jung F, Haberkant P, Stein F, Wollweber F, Gackstatter A, Zöller E, van der Laan M, Savitski MM, Benes V, Herrmann JM. Nat Cell Biol. 2019 Jun;21(6):793-794. doi: 10.1038/s41556-019-0326-1.

May

Cochlea-Specific Deletion of Cav1.3 Calcium Channels Arrests Inner Hair Cell Differentiation and Unravels Pitfalls of Conditional Mouse Models. Eckrich S, Hecker D, Sorg K, Blum K, Fischer K, Münkner S, Wenzel G, Schick B, Engel J. Front Cell Neurosci. 2019 May 22, 13:225. doi: 10.3389/fncel.2019.00225.

Dynamic assembly of ribbon synapses and circuit maintenance in a vertebrate sensory system. Okawa H, Yu WQ, Matti U, Schwarz K, Odermatt B, Zhong H, Tsukamoto Y, Lagnado L, Rieke F, Schmitz F, Wong ROL. Nat Commun. 2019 May 15;10(1):2167. doi: 10.1038/s41467-019-10123-1.

April

Activation of the calcium-sensing receptor attenuates TRPV6-dependent intestinal calcium absorption. Lee JJ, Liu X, O'Neill D, Beggs MR, Weissgerber P, Flockerzi V, Chen XZ, Dimke H, Alexander RT. JCI Insight. 2019 Apr 23;5. pii: 128013. doi: 10.1172/jci.insight.128013.

March

The SNAP-25 linker supports fusion intermediates by local lipid interactions. Shaaban A, Dhara M, Frisch W, Harb A, Shaib AH, Becherer U, Bruns D, Mohrmann R. Elife. 2019 Mar 18;8. pii: e41720. doi: 10.7554/eLife.41720.

February

Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca²⁺ Leakage from the Endoplasmic Reticulum. Gamayun I, O’Keefe,S, Pick T, Klein MC, Nguyen D, McKibbin C, Piacenti M, Williams HM, Flitsch SL, Whitehead RC, Swanton E, Helms V, High S, Zimmermann R, Cavalie A. Cell Chem Biol. 2019 Apr 18;26(4):571-583.e6. doi: 10.1016/j.chembiol.2019.01.010.

Central role of G protein Gαi2 and Gαi vomeronasal neurons in balancing territorial and infant-directed aggression of male mice. Trouillet AC, Keller M, Weiss J, Leinders-Zufall T, Birnbaumer L, Zufall F, Chamero P. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5135-5143. doi: 10.1073/pnas.1821492116.

CaMKII does not control mitochondrial Ca²⁺ uptake in cardiac myocytes. Nickel AG, Kohlhaas M, Bertero E, Wilhelm D, Wagner M, Sequeira V, Kreusser MM, Dewenter M, Kappl R, Hoth M, Dudek J, Backs J, Maack C. J Physiol. 2019 Feb 16. doi: 10.1113/JP276766.

The kidney anion exchanger 1 affects tight junction properties via claudin-4. Lashhab R, Rumley AC, Arutyunov D, Rizvi M, You C, Dimke H, Touret N, Zimmermann R, Jung M, Chen XZ, Alexander T, Cordat E. Sci Rep. 2019 Feb 28;9(1):3099. doi: 10.1038/s41598-019-39430-9.

Cytotoxicity of new psychoactive substances and other drugs of abuse studied in human HepG2 cells using an adopted high content screening assay>. Richter LHJ, Beck A, Flockerzi V, Maurer HH, Meyer MR. Toxicol Lett. 2019 Feb;301:79-89. doi: 10.1016/j.toxlet.2018.11.007. Epub 2018 Nov 19.

January

Identification of Inhibitory Ca²⁺ Binding Sites in the Upper Vestibule of the Yeast Vacuolar TRP Channel. Amini M, Wang H, Belkacemi A, Jung M, Bertl A, Schlenstedt G, Flockerzi V, Beck A. iScience. 2019 Jan 25; 11: 1–12, doi: 10.1016/j.isci.2018.11.037.

miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling. Hart M, Walch-Rückheim B, Friedmann KS, Rheinheimer S, Tänzer T, Glombitza B, Sester M, Lenhof HP, Hoth M, Schwarz EC, Keller A, Meese E. Cell Death Dis. 2019 Jan 18;10(2):46. doi: 10.1038/s41419-018-1295-1.

Calcium signal dynamics in T lymphocytes: Comparing in vivo and in vitro measurements. Friedmann KS, Bozem M, Hoth M. Semin Cell Dev Biol. 2019 Jan 10. pii: S1084-9521(18)30055-7. doi: 10.1016/j.semcdb.2019.01.004.

The Role of Plastidic Trigger Factor Serving Protein Biogenesis in Green Algae and Land Plants. Rohr M, Ries F, Herkt C, Gotsmann VL, Westrich LD, Gries K, Trösch R, Christmann J, Chaux-Jukic F, Jung M, Zimmer D, Mühlhaus T, Sommer F, Schroda M, Keller S, Möhlmann T, Willmund F. Plant Physiol. 2019 Mar;179(3):1093-1110. doi: 10.1104/pp.18.01252.

An alternative exon of CAPS2 influences catecholamine loading into LDCVs of chromaffin cells. Ratai O, Schirra C, Rajabov E, Brunk I, Ahnert-Hilger G, Chitirala P, Becherer U, Stevens DR, Rettig J. J Neurosci. 2019 Jan 2;39(1):18-27. doi: 10.1523/JNEUROSCI.2040-18.2018.