Publications 2017


An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases. Lang S, Pfeffer S, Lee P-H, Cavalié A, Helms V, Förster F,  Zimmermann R.  Front Physiol. 2017 Nov 1;8:887. doi: 10.3389/fphys.2017.00887.

Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways. Schwarz Y, Zhao N, Kirchhoff F, Bruns D. 25. Nat Neurosci. 2017 Nov;20(11):1529-1539. doi: 10.1038/nn.4647.


hSnd2 protein represents an alternative targeting factor to the endoplasmic reticulum in human cells. Haßdenteufel S, Sicking M, Schorr S, Aviram N, Fecher-Trost C, Schuldiner M, Jung M, Zimmermann R, Lang S. FEBS Lett. 2017 Oct;591(20):3211-3224. doi: 10.1002/1873-3468.12831. 

Structural basis for substrate selection by the translocation and assembly module of the beta-barrel assembly machinery. Bamert RS, Lundquist K, Hwang H, Webb CT, Shiota T, Stubenrauch CJ, Belousoff MJ, Goode RJA, Schittenhelm RB, Zimmermann RJung M, Gumbart JC, Lithgow T. Mol Microbiol. 2017 Oct;106(1):142-156. doi: 10.1111/mmi.13757.


NFATc1 controls the cytotoxicity of CD8+ T cells. Klein-Hessling S, Muhammad K, Klein M, Pusch T, Rudolf R, Flöter J, Qureischi M, Beilhack A, Vaeth M, Kummerow C, Backes C, Schoppmeyer R, Hahn U, Hoth M,  Bopp T, Berberich-Siebelt F, Patra A, Avots A, Müller N, Schulze A, Serfling E. Nat Commun. 2017 Sep 11;8(1):511. doi: 10.1038/s41467-017-00612-6.


Mitochondrial energetics and calcium coupling in the heart. Kohlhaas M, Nickel AG, Maack CJ Physiol. 2017 Jun 15;595(12):3753-3763. doi: 10.1113/JP273609. 


An easy, fast and “low-tech”-equipment-requiring alternative method to optimize immunolabelling conditions for pre-embedding immunogold electron microscopy and to correlate light and electron microscopical immunogold labelling results . Suiwal S, Kiefer G, Schmitz F, Schwarz K.  J Immunol Methods. 2017 May;444:7-16. doi: 10.1016/j.jim.2017.02.003.


Lets talk about Secs: Sec61, Sec62, Sec63 in signal transduction, oncology and personalized medicine. Linxweiler M, Schick B, Zimmermann R. Signal Transduct Target Ther. 2017 Apr 28;2:17002. doi: 10.1038/sigtrans.2017.2. 

Organization and Plasticity of Sodium Channel Expression in the Mouse Olfactory and Vomeronasal Epithelia. Bolz F, Kasper S, Bufe B, Zufall F, Pyrski M. Front Neuroanat. 2017 Apr 3;11:28. doi: 10.3389/fnana.2017.00028. 

Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia. . Jahn HM, Kasakow CV, Helfer A, Michely J, Verkhratsky A, Maurer HH, Scheller A, Kirchhoff F.  Sci Rep. 2018 Apr 12;8(1):5913. doi: 10.1038/s41598-018-24085-9.


Simultaneous Membrane Capacitance Measurements and TIRF Microscopy to Study Granule Trafficking at Immune Synapses. Sleiman M, Stevens DR, Rettig JMethods Mol Biol. March, 3 2017;1584:157-169. doi: 10.1007/978-1-4939-6881-7_11.

Electrochemical Quantification of Extracellular Local H2O2 Kinetics Originating from Single Cells. Bozem M, Knapp P, Mirceski V, Slowik E, Bogeski I, Kappl R, Heinemann C, Hoth M. Antioxid Redox Signal. 2017 Mar 17. doi: 10.1089/ars.2016.6840.

RIBEYE(B)-domain binds to lipid components of synaptic vesicles in an NAD(H)-dependent, redox-sensitive manner. Schwarz K, Schmitz F. Biochem J. 2017 Mar 20;474(7):1205-1220. doi: 10.1042/BCJ20160886.

Does Erythropoietin Regulate TRPC Channels in Red Blood Cells? Danielczok J, Hertz L, Ruppenthal S, Kaiser E, Petkova-Kirova P, Bogdanova A, Krause E, Lipp P, Freichel M, Kaestner L, Birnbaumer L. Cell Physiol Biochem. 2017 Mar 6;41(3):1219-1228. doi: 10.1159/000464384. 

Large dense-core vesicle exocytosis from mouse dorsal root ganglion neurons is regulated by neuropeptide Y. Bost A, Shaib AH, Schwarz Y, Niemeyer BA, Becherer U.  Neuroscience. 2017 Mar 27;346:1-13. doi: 10.1016/j.neuroscience.2017.01.006.


Dissecting the molecular organization of the translocon-associated protein complex. Pfeffer S, Dudek J, Schaffer M, Ng BG, Albert S, Plitzko JM, Baumeister W, Zimmermann R, Freeze HH, Engel BD, Förster F. Nat Commun. 2017 Feb 20;8:14516. doi: 10.1038/ncomms14516.

Endogenous nitric oxide formation in cardiac myocytes does not control respiration during β-adrenergic stimulation. Kohlhaas M, Nickel AG, Bergem S, Casadei B, Laufs U, Maack C. J Physiol. 2017 Feb 22. doi: 10.1113/JP273750.

Metabolic cardiomyopathies - fighting the next epidemic. Maack C, Murphy E. Cardiovasc Res. 2017 Feb 16. doi: 10.1093/cvr/cvx022.

Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy. Stapel B, Kohlhaas M, Ricke-Hoch M, Haghikia A, Erschow S, Knuuti J, Silvola JM, Roivainen A, Saraste A, Nickel AG, Saar JA, Sieve I, Pietzsch S, Müller M, Bogeski I, Kappl R, Jauhiainen M, Thackeray JT, Scherr M, Bengel FM, Hagl C, Tudorache I, Bauersachs J, Maack C, Hilfiker-Kleiner D. Eur Heart J. 2017 Feb 1;38(5):349-361. doi: 10.1093/eurheartj/ehw086.

Mitochondrial Therapies in Heart Failure. von Hardenberg A, Maack C. Handb Exp Pharmacol. 2017 Feb 9. doi: 10.1007/164_2016_123.

Barth syndrome cardiomyopathy. Dudek J, Maack C. Cardiovasc Res. 2017 Feb 2. doi: 10.1093/cvr/cvx014.


Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas. Bochen F, Adisurya H, Wemmert S, Lerner C, Greiner M, Zimmermann R, Hasenfus A, Wagner M, Smola S, Pfuhl T, Bozzato A, Al Kadah B, Schick B, Linxweiler M. Oncotarget. 2017 Jan 17;8(3):4922-4934. doi: 10.18632/oncotarget.13986.

Identification of Sidt2 as a lysosomal cation-conducting protein. Beck A, Fecher-Trost C, Wolske K, Philipp SE, Flockerzi V, Wissenbach U.  FEBS Lett. 2017 Jan;591(1):76-87. doi: 10.1002/1873-3468.12528.