December

Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Ertürk A, Mauch CP, Hellal F, Förstner F, Keck T, Becker K, Jährling N, Steffens H, Richter M, Hübener M, Kramer E, Kirchhoff F, Dodt HU, Bradke F. Nat Med. 2011 Dec 25;18(1):166-71. doi: 10.1038/nm.2600. 

November

The synaptic ribbon is a site of phosphatidic acid generation in ribbon synapses. Schwarz K, Natarajan S, Kassas N, Vitale N, Schmitz F. J Neurosci. 2011 Nov 2;31(44):15996-6011. doi: 10.1523/JNEUROSCI.2965-11.2011.

Redox regulation of calcium ion channels: chemical and physiological aspects. Bogeski I, Kappl R, Kummerow C, Gulaboski R, Hoth M, Niemeyer BA. Cell Calcium. 2011 Nov;50(5):407-23. doi: 10.1016/j.ceca.2011.07.006.

Melanopsin signalling in mammalian iris and retina. Xue T, Do MT, Riccio A, Jiang Z, Hsieh J, Wang HC, Merbs SL, Welsbie DS, Yoshioka T, Weissgerber P, Stolz S, Flockerzi V, Freichel M, Simon MI, Clapham DE, Yau KW. Nature. 2011 Nov 2;479(7371):67-73. doi: 10.1038/nature10567.

September

Newborn interneurons in the accessory olfactory bulb promote mate recognition in female mice. Oboti L, Schellino R, Giachino C, Chamero P, Pyrski M, Leinders-Zufall T, Zufall F, Fasolo A, Peretto P. Front Neurosci. 2011 Sep 28;5:113. doi: 10.3389/fnins.2011.00113.

ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance. Qu B, Al-Ansary D, Kummerow C, Hoth M, Schwarz EC. Cell Calcium. 2011 Sep;50(3):261-9. doi: 10.1016/j.ceca.2011.05.015.

Excitable T cells: Ca(v)1.4 channel contributions and controversies. Niemeyer BA, Hoth M. Immunity. 2011 Sep 23;35(3):315-7. doi: 10.1016/j.immuni.2011.09.001

August

G protein G{alpha}o is essential for vomeronasal function and aggressive behavior in mice. Chamero P, Katsoulidou V, Hendrix P, Bufe B, Roberts R, Matsunami H, Abramowitz J, Birnbaumer L, Zufall F, Leinders-Zufall T. Proc Natl Acad Sci USA. 2011 Aug 2;108(31):12898-903. doi: 10.1073/pnas.1107770108.

A monoclonal antibody for in vivo detection of peroxisome-associated PTS1 receptor. Cizmowski C, Jung M, Erdmann R, Schliebs W. Hybridoma (Larchmt). 2011 Aug;30(4):387-91. doi: 10.1089/hyb.2011.0038.

In Situ Visualization of Protein Interactions in Sensory Neurons: Glutamic Acid-Rich Proteins (GARPs) Play Differential Roles for Photoreceptor Outer Segment Scaffolding. Ritter LM, Khattree N, Tam B, Moritz OL, Schmitz F, Goldberg AF. J Neurosci. 2011 Aug 3;31(31):11231-43. doi: 10.1523/JNEUROSCI.2875-11.2011.

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation. Quintana A, Pasche M, Junker C, Al-Ansary D, Rieger H, Kummerow C, Nuñez L, Villalobos C, Meraner P, Becherer U, Rettig J, Niemeyer BA, Hoth M. EMBO J. 2011 Aug 16;30(19):3895-912. doi: 10.1038/emboj.2011.289.

July

Calmodulin regulation of the calcium-leak channel Sec61 is unique to vertebrates. Harsman A, Kopp A, Wagner R, Zimmermann R, Jung M. Channels (Austin). 2011 Jul-Aug;5(4):293-8.

Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes. Pattu V, Qu B, Marshall M, Becherer U, Junker C, Matti U, Schwarz EC, Krause E, Hoth M, Rettig J. Traffic. 2011 Jul;12(7):890-901. doi: 10.1111/j.1600-0854.2011.01193.x.

Sec62 protein level is crucial for the ER stress tolerance of prostate cancer. Greiner M, Kreutzer B, Lang S, Jung V, Cavalié A, Unteregger G, Zimmermann R, Wullich B. Prostate. 2011 Jul;71(10):1074-83. doi: 10.1002/pros.21324.

Live cell calcium imaging combined with siRNA mediated gene silencing identifies Ca²⁺ leak channels in the ER membrane and their regulatory mechanisms. Lang S, Schäuble N, Cavalié A, Zimmermann R. J Vis Exp. 2011 Jul 7;(53):e2730. doi: 10.3791/2730.

Juni

Docking of Lytic Granules at the Immunological Synapse in Human CTL Requires Vti1b-Dependent Pairing with CD3 Endosomes. Qu B, Pattu V, Junker C, Schwarz EC, Bhat SS, Kummerow C, Marshall M, Matti U, Neumann F, Pfreundschuh M, Becherer U, Rieger H, Rettig J, Hoth M. J Immunol. 2011 Jun 15;186(12):6894-904. doi: 10.4049/jimmunol.1003471. 

Calcium binding and transport by Coenzyme Q. Bogeski I, Gulaboski R, Kappl R, Mirceski VB, Stefova M, Petreska J, Hoth M. J Am Chem Soc. 2011 Jun 22;133(24):9293-303. doi: 10.1021/ja110190t.

Targeting Mitochondrial Oxidative Stress in Heart Failure Throttling the Afterburner. Maack C, Böhm M. J Am Coll Cardiol. 2011 Jun 28;58(1):83-6. doi: 10.1016/j.jacc.2011.01.032. 

A role for glia in the progression of Rett's syndrome. Lioy DT, Garg SK, Monaghan CE, Raber J, Foust KD, Kaspar BK, Hirrlinger PG, Kirchhoff F, Bissonnette JM, Ballas N, Mandel G. Nature. 2011 Jun 29;475(7357):497-500. doi: 10.1038/nature10214. 

Female reproductive maturation in the absence of kisspeptin/GPR54 signaling. Mayer C, Boehm U. Nat Neurosci. 2011 Jun;14(6):704-10. doi: 10.1038/nn.2818.

May

Sec61 complexes form ubiquitous ER Ca²⁺ leak channels. Lang S, Erdmann F, Jung M, Wagner R, Cavalié A, Zimmermann R. Channels (Austin). 2011 May-Jun;5(3):228-35.

Male fertility depends on Ca²⁺ absorption by TRPV6 in epididymal epithelia. Weissgerber P, Kriebs U, Tsvilovskyy V, Olausson J, Kretz O, Stoerger C, Vennekens R, Wissenbach U, Middendorff R, Flockerzi V, Freichel M. Sci Signal. 2011 May 3;4(171):ra27. doi: 10.1126/scisignal.2001791.

Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the CACNB2 gene. Meissner M, Weissgerber P, Camacho Londono JE, Prenen J, Link S, Ruppenthal S, Molkentin JD, Lipp P, Nilius B, Freichel M, Flockerzi V. J Biol Chem. 2011 May 6;286(18):15875-82. doi: 10.1074/jbc.M111.227819.

TRPM3 is a nociceptor channel involved in the detection of noxious heat. Vriens J, Owsianik G, Hofmann T, Philipp SE, Stab J, Chen X, Benoit M, Xue F, Janssens A, Kerselaers S, Oberwinkler J, Vennekens R, Gudermann T, Nilius B, Voets T. Neuron. 2011 May 12;70(3):482-94. doi: 10.1016/j.neuron.2011.02.051.

April

Immune synapses: mitochondrial morphology matters. Junker C, Hoth M. EMBO J. 2011 Apr 6;30(7):1187-9. doi: 10.1038/emboj.2011.72

Transient Receptor Potential Melastatin 1 (TRPM1) Is an Ion-conducting Plasma Membrane Channel Inhibited by Zinc Ions. Lambert S, Drews A, Rizun O, Wagner TF, Lis A, Mannebach S, Plant S, Portz M, Meissner M, Philipp SE, Oberwinkler J. J Biol Chem. 2011 Apr 8;286(14):12221-33. doi: 10.1074/jbc.M110.202945.

Transport of the Major Myelin Protein PLP is Directed by the R-SNAREs VAMP3 and VAMP7. Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, Krämer-Albers EM. J Neurosci. 2011 Apr 13;31(15):5659-72. doi: 10.1523/JNEUROSCI.6638-10.2011.

Loss-of-function mutations in sodium channel Na(v)1.7 cause anosmia. Weiss J, Pyrski M, Jacobi E, Bufe B, Willnecker V, Schick B, Zizzari P, Gossage SJ, Greer CA, Leinders-Zufall T, Woods CG, Wood JN, Zufall F. Nature. 2011 Apr 14;472(7342):186-90. doi: 10.1038/nature09975.

Genetic identification of GnRH receptor neurons: a new model for studying neural circuits underlying reproductive physiology in the mouse brain. Wen S, Götze IN, Mai O, Schauer C, Leinders-Zufall T, Boehm U. Endocrinology. 2011 Apr;152(4):1515-26. doi: 10.1210/en.2010-1208.

Interplay of defective excitation-contraction coupling, energy starvation, and oxidative stress in heart failure. Kohlhaas M, Maack C. Trends Cardiovasc Med. 2011 Apr;21(3):69-73. doi: 10.1016/j.tcm.2012.03.002.

February

Vesicle pools: lessons from adrenal chromaffin cells. Stevens DR, Schirra C, Becherer U, Rettig J. Front Synaptic Neurosci. 2011 Feb 1;3:2. doi: 10.3389/fnsyn.2011.00002.

January

Interaction of calmodulin with Sec61α limits Ca²⁺ leakage from the endoplasmic reticulum. Erdmann F, Schäuble N, Lang S, Jung M, Honigmann A, Ahmad M, Dudek J, Benedix J, Harsman A, Kopp A, Helms V, Cavalié A, Wagner R, Zimmermann R. EMBO J. 2011 Jan 5;30(1):17-31. doi: 10.1038/emboj.2010.284.

Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness. Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nürnberg P, Striessnig J, Bolz HJ. Nat Neurosci. 2011 Jan;14(1):77-84. doi: 10.1038/nn.2694.

Others

Lessons of studying TRP channels with antibodies. In TRP channels, CRC methods in signal transduction series. Meissner M, Obmann VC, Hoschke M, Link S, Jung M, Held G, Philipp SE, Zimmermann R, Flockerzi V. M. X. Zhu, ed. 2011 CRC Press, New York, 135-148.

Strategies and Protocols to Generate Mouse Models with Targeted Mutations to Analyze TRP Channel Functions. Freichel M, Kriebs U, Vogt D, Mannebach S, Weissgerber P. In: Zhu MX, editor. SourceTRP Channels. Boca Raton (FL): CRC Press; 2011. Chapter 8.