Project A10 - Varsha Pattu & Jens Rettig
Cytotoxic T lymphocyte function in vitro and in vivo
We could show that endocytosis of cytotoxic granules contributes significantly to the killing capacity of cytotoxic T lymphocytes. With the help of lipid bilayer TIRF microscopy we will continue to investigate the molecular mechanism of endocytosis, including the Ca2+ and lipid dependence, on the single granule level.
Furthermore, we will study T cell function in an in vivo model, the anterior chamber of the eye.
Universität des Saarlandes
Institut für Physiologie
CIPMM | Gebäude 48