Ca2+-Signale:
Molekulare Mechanismen und Integrative Funktionen
Sonder­forschungs­bereich 894

Publikationen 2018

November

An alternative exon of CAPS2 influences catecholamine loading into LDCVs of chromaffin cells. Ratai O, Schirra C, Rajabov E, Brunk I, Ahnert-Hilger G, Chitirala P, Becherer U, Stevens DR, Rettig J.  J Neurosci. 2018 Nov 2. pii: 2040-18. doi: 10.1523/JNEUROSCI.2040-18.2018.

August

AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum. Klein MC, Zimmermann K, Schorr S, Landini M, Klemens PAW, Altensell J, Jung M, Krause E, Nguyen D, Helms V, Rettig J, Fecher-Trost C, Cavalié A, Hoth M, Bogeski I, Neuhaus HE, Zimmermann R, Lang S, Haferkamp I.  Nat Commun. 2018 Aug 28;9(1):3489. doi: 10.1038/s41467-018-06003-9.

Electrochemical Quantification of Extracellular Local H2O2 Kinetics Originating from Single Cells. Bozem M, Knapp P, Mirčeski V, Slowik EJ, Bogeski I, Kappl R, Heinemann C, Hoth M. Antioxid Redox Signal. 2018 Aug 20;29(6):501-517. doi: 10.1089/ars.2016.6840.

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate. Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M.  Nat Med. 2018 Aug;24(8):1192-1203. doi: 10.1038/s41591-018-0095-6.

Juli

A mechanism for exocytotic arrest by the Complexin C-terminus. Makke M, Mantero Martinez M, Gaya S, Schwarz Y, Frisch W, Silva-Bermudez L, Jung M, Mohrmann R, Dhara M, Bruns D.  Elife. 2018 Jul 25;7. pii: e38981. doi: 10.7554/eLife.38981.

Fast Ca2+ Transients of Inner Hair Cells Arise Coupled and Uncoupled to Ca2+ Waves of Inner Supporting Cells in the Developing Mouse Cochlea.  Eckrich T, Blum K, Milenkovic I, Engel JFront Mol Neurosci. 2018 Jul 30;11:264. doi: 10.3389/fnmol.2018.00264.

Ca2+-dependent regulation and binding of calmodulin to multiple sites of Transient Receptor Potential Melastatin 3 (TRPM3) ion channels. Przibilla J, Dembla S, Rizun O, Lis A, Jung M, Oberwinkler J, Beck A, Philipp SE. Cell Calcium 2018 Jul;73:40-52. doi: 10.1016/j.ceca.2018.03.005. 

A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity. Zhou X, Friedmann KS, Lyrmann H, Zhou Y, Schoppmeyer R, Knörck A, Mang S, Hoxha C, Angenendt A, Backes CS, Mangerich C, Zhao R, Cappello S, Schwär G, Hässig C, Neef M, Bufe B, Zufall F, Kruse K, Niemeyer BA, Lis A, Qu B, Kummerow C, Schwarz EC, Hoth M. J Physiol 2018 Jul;596(14):2681-2698. doi: 10.1113/JP274964. 

Juni

Quantity, quality, and functionality of peripheral blood cells derived from residual blood of different apheresis kits.. Knörck A, Marx S, Friedmann KS, Zöphel S, Lieblang L, Hässig C, Müller I, Pilch J, Sester U, Hoth M, Eichler H, Sester M, Schwarz EC. Transfusion. 2018 Jun;58(6):1516-1526. doi: 10.1111/trf.14616.

Light-sheet Microscopy for Three-dimensional Visualization of Human Immune Cells.. Schoppmeyer R, Zhao R, Hoth M, Qu B.  J Vis Exp. 2018 Jun 13;(136). doi: 10.3791/57651.

Mai

Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier. Haßdenteufel S, Johnson N, Paton AW, Paton JC, High S, Zimmermann R. (2018) Cell Rep. 2018 May 1;23(5):1373-1386. doi: 10.1016/j.celrep.2018.03.122.

Treatment of SEC62 over-expressing tumors by Thapsigargin and Trifluoperazine. Körbel C, Linxweiler M, Bochen F, Wemmert S, Schick B, Meyer M, Maurer H, Menger MD, Zimmermann R, Greiner M.  Biomol Concepts. 2018 May 19;9(1):53-63. doi: 10.1515/bmc-2018-0006..

April

Plasma cell deficiency in humans with heterozygous mutations in SEC61A1. Schubert D, Klein MC, Hassdenteufel S, Caballero-Oteyza A, Yang L, Proietti M, Bulashevska A, Kemming J, Kühn J, Winzer S, Rusch S, Fliegauf M, Schäffer A, Pfeffer S, Geiger R, Cavalié A, Cao H, Yang F, Li Y, Rizzi M, Eibel H, Kobbe R, Marks A, Peppers BP, Hostoffer RW, Puck JM, Zimmermann R, Grimbacher B.  J Allergy Clin Immunol. 2018 Apr;141(4):1427-1438. doi: 10.1016/j.jaci.2017.06.042.

Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences.  Backes S, Hess S, Boos F, Woellhaf MW, Gödel S, Jung M, Mühlhaus T, Herrmann JM.  J Cell Biol. 2018 Apr 2;217(4):1369-1382. doi: 10.1083/jcb.201708044.

Cross-linking of Orai1 channels by STIM proteins. Zhou Y, Nwokonko RM, Cai X, Loktionova NA, Xin P, Trebak M, Niemeyer BA, Wang Y, Gill DL. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3398-E3407. doi: 10.1073/pnas.1720810115.

Februar

Cytotoxic granule endocytosis depends on the Flower protein. Chang HF, Mannebach S, Beck A, Ravichandran K, Krause E, Frohnweiler K, Fecher-Trost C, Schirra C, Pattu V, Flockerzi V, Rettig J. J Cell Biol. 2018 Feb 5;217(2):667-683. doi: 10.1083/jcb.201706053.

Januar

IP3 Receptor-Dependent Cytoplasmic Ca2+ Signals Are Tightly Controlled by Cavβ3. Belkacemi A, Hui X, Wardas B, Laschke MW, Wissenbach U, Menger MD,  Lipp P, Beck A, Flockerzi V. Cell Rep. 2018 Jan 30;22(5):1339-1349. doi: 10.1016/j.celrep.2018.01.010.

v-SNARE function in chromaffin cells. Dhara M, Mohrmann R, Bruns D. Pflugers Arch. 2018 Jan;470(1):169-180. doi: 10.1007/s00424-017-2066-z.