Ca2+-Signale:
Molekulare Mechanismen und Integrative Funktionen
Sonder­forschungs­bereich 894

Publikationen 2016

Dezember

A Sensor for Low Environmental Oxygen in the Mouse Main Olfactory Epithelium. Bleymehl K, Pérez-Gómez A, Omura M, Moreno-Pérez A, Macías D, Bai Z, Johnson RS, Leinders-Zufall T, Zufall F, Mombaerts P. Neuron. 2016 Dec 21;92(6):1196-1203. doi: 10.1016/j.neuron.2016.11.001.

Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks. Perea G, Gómez R, Mederos S, Covelo A, Ballesteros JJ, Schlosser L, Hernández-Vivanco A, Martín-Fernández M, Quintana R, Rayan A, Díez A, Fuenzalida M, Agarwal A, Bergles DE, Bettler B, Manahan-Vaughan D, Martín ED, Kirchhoff F, Araque A. Elife. 2016 Dec 24;5. pii: e20362. doi: 10.7554/eLife.20362.

November

The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Aviram N, Ast T, Costa EA, Arakel EC, Chuartzman SG, Jan CH, Haßdenteufel S, Dudek J, Jung M, Schorr S, Zimmermann R, Schwappach B, Weissman JS, Schuldiner M. Nature. 2016. 540, 134-138. doi:10.1038/nature20169

Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery. Fumagalli F, Noack J, Bergmann TJ, Presmanes EC, Pisoni GB, Fasana E, Fregno I, Galli C, Loi M, Soldà T, D'Antuono R, Raimondi A, Jung M, Melnyk A, Schorr S, Schreiber A, Simonelli L, Varani L, Wilson-Zbinden C, Zerbe O, Hofmann K, Peter M, Quadroni M, Zimmermann R, Molinari M. Nat Cell Biol. 2016 Nov;18(11):1173-1184. doi: 10.1038/ncb3423.

Oktober

α2δ2 Controls the Function and Trans-Synaptic Coupling of Cav1.3 Channels in Mouse Inner Hair Cells and Is Essential for Normal Hearing. Fell B, Eckrich S, Blum K, Eckrich T, Hecker D, Obermair GJ, Münkner S, Flockerzi V, Schick B, Engel J. J Neurosci. 2016 Oct 26;36(43):11024-11036.

September

Preparing the lethal hit: interplay between exo- and endocytic pathways in cytotoxic T lymphocytes. Chang HF, Bzeih H, Chitirala P, Ravichandran K, Sleiman M, Krause E, Hahn U, Pattu VRettig JCell Mol Life Sci. 2016 Sep 1. doi: 10.1007/s00018-016-2350-7.

August

Endocytosis of Cytotoxic Granules Is Essential for Multiple Killing of Target Cells by T Lymphocytes. Chang HF, Bzeih H, Schirra C, Chitirala P, Halimani M, Cordat E, Krause E, Rettig J, Pattu V. J Immunol. 2016 Aug 15. pii: 1600828.

Juli

Endocannabinoids and Heterogeneity of Glial Cells in Brain Function. Scheller A, Kirchhoff F. Front Integr Neurosci. 2016 Jul 5;10:24. doi: 10.3389/fnint.2016.00024.

Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes. Bhat SS, Friedmann KS, Knörck A, Hoxha C, Leidinger P, Backes C, Meese E, Keller A, Rettig J, Hoth M, Qu B, Schwarz EC. Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1653-64. doi: 10.1016/j.bbamcr.2016.04.014.

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism. Saab AS, Tzvetavona ID, Trevisiol A, Baltan S, Dibaj P, Kusch K, Möbius W, Goetze B, Jahn HM, Huang W, Steffens H, Schomburg ED, Pérez-Samartín A, Pérez-Cerdá F, Bakhtiari D, Matute C, Löwel S, Griesinger C, Hirrlinger J, Kirchhoff F, Nave KA. Neuron. 2016 Jul 6;91(1):119-32. doi: 10.1016/j.neuron.2016.05.016.

The inhibitory input to mouse cerebellar Purkinje cells is reciprocally modulated by Bergmann glial P2Y1 and AMPA receptor signaling. Rudolph R, Jahn HM, Courjaret R, Messemer N, Kirchhoff F, Deitmer JW. Glia. 2016 Jul;64(7):1265-80. doi: 10.1002/glia.22999.

Juni

v-SNARE transmembrane domains function as catalysts for vesicle fusion. Dhara M, Yarzagaray A, Makke M, Schindeldecker B, Schwarz Y, Shaaban A, Sharma S, Böckmann RA, Lindau M, Mohrmann R, Bruns D. Elife. 2016 Jun 25;5. pii: e17571. doi: 10.7554/eLife.17571.

The sensing of bacteria: emerging principles for the detection of signal sequences by formyl peptide receptors. Bufe B, Zufall F. Biomol Concepts. 2016 Jun 1;7(3):205-14. doi: 10.1515/bmc-2016-0013.

Mai

How to make a synaptic ribbon: RIBEYE deletion abolishes ribbons in retinal synapses and disrupts neurotransmitter release. Maxeiner S, Luo F, Tan A, Schmitz F, Südhof TC. EMBO J. 2016 May 17;35(10):1098-114. doi: 10.15252/embj.201592701. 

Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control. Djogo T, Robins SC, Schneider S, Kryzskaya D, Liu X, Mingay A, Gillon CJ, Kim JH, Storch KF, Boehm U, Bourque CW, Stroh T, Dimou L, Kokoeva MV. Cell Metab. 2016 May 10;23(5):797-810. doi: 10.1016/j.cmet.2016.04.013.

Functional Overexpression of Vomeronasal Receptors Using a Herpes Simplex Virus Type 1 (HSV-1)-Derived Amplicon. Stein B, Alonso MT, Zufall F, Leinders-Zufall T, Chamero P. PLoS One. 2016 May 19;11(5):e0156092. doi: 10.1371/journal.pone.0156092.

April

Transient Receptor Potential A1 (TRPA1) Channels regulate Epithelial Cell Barriers formed by MDCK Cells. Dembla S, Hasan N, Becker A, Beck A, Philipp SEFEBS Lett. 2016 Apr 21. doi: 10.1002/1873-3468.12183.

The cardiac re-AKT-ion to chronic volume overload. Maack CEur J Heart Fail. 2016 Apr;18(4):372-4. doi: 10.1002/ejhf.523.

Leptin receptor null mice with re-expression of LepR in GnRH-R expressing cells display elevated FSH levels but remain in a prepubertal state. Allen SJ, Garcia-Galiano D, Borges BC, Burger LL, Boehm U, Elias CF. Am J Physiol Regul Integr Comp Physiol. 2016 Apr 13:ajpregu.00529.2015. doi: 10.1152/ajpregu.00529.2015.

Estradiol Restrains Prepubertal Gonadotropin Secretion in Female Mice via Activation of ERα in Kisspeptin Neurons. Dubois SL, Wolfe A, Radovick S, Boehm U, Levine JE. Endocrinology. 2016 Apr;157(4):1546-54. doi: 10.1210/en.2015-1923.

März

Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy. Stapel B, Kohlhaas M, Ricke-Hoch M, Haghikia A, Erschow S, Knuuti J, Silvola JM, Roivainen A, Saraste A, Nickel AG, Saar JA, Sieve I, Pietzsch S, Müller M, Bogeski I, Kappl R, Jauhiainen M, Thackeray JT, Scherr M, Bengel FM, Hagl C, Tudorache I, Bauersachs J, Maack C, Hilfiker-Kleiner D. Eur Heart J. 2016 Mar 21. pii: ehw086.

Normal gonadotropin production and fertility in gonadotrope-specific BMPR1A knockout mice. Zhou X, Wang Y, Ongaro L, Boehm U, Kaartinen V, Mishina Y, Bernard DJ. J Endocrinol. 2016 Mar 30. pii: JOE-16-0053.

Pannexin-1 channels show distinct morphology and no gap junction characteristics in mammalian cells. Beckmann A, Grissmer A, Krause E, Tschernig T, Meier C. Cell Tissue Res. 2016 Mar;363(3):751-63. doi: 10.1007/s00441-015-2281-x.

A reliable method for quantification of splice variants using RT-qPCR. Camacho Londoño J, Philipp SE. BMC Mol Biol. 2016 Mar 15;17(1):8. doi: 10.1186/s12867-016-0060-1.

Strain-specific loss of formyl peptide receptor 3 in the murine vomeronasal and immune systems. Stempel H, Jung M, Pérez-Goméz A, Leinders-Zufall T, Zufall F, Bufe B. J Biol Chem. 2016 Mar 8. pii: jbc.M116.714493.

Molecular Plasticity of Male and Female Murine Gonadotropes Revealed by mRNA Sequencing. Qiao S, Nordström K, Muijs L, Gasparoni G, Tierling S, Krause E, Walter J, Boehm U. Endocrinology. 2016 Mar;157(3):1082-93. doi: 10.1210/en.2015-1836.

Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry. Dörr K, Kilch T, Kappel S, Alansary D, Schwär G, Niemeyer BA, Peinelt C. Sci Signal. 2016 Mar 8;9(418):ra25. doi: 10.1126/scisignal.aaa9913.

Februar

Evaluation of TgH(CX3CR1-EGFP) mice implanted with mCherry-GL261 cells as an in vivo model for morphometrical analysis of glioma-microglia interaction. Resende FF, Bai X, Del Bel EA, Kirchhoff F, Scheller A, Titze-de-Almeida R. BMC Cancer. 2016 Feb 8;16(1):72. doi: 10.1186/s12885-016-2118-3.

Deep characterization of blood cell miRNomes by NGS. Schwarz EC, Backes C, Knörck A, Ludwig N, Leidinger P, Hoxha C, Schwär G, Grossmann T, Müller SC, Hart M, Haas J, Galata V, Müller I, Fehlmann T, Eichler H, Franke A, Meder B, Meese E, Hoth M, Keller A. Cell Mol Life Sci. 2016 Feb 13. PMID: 26874686

Changing calcium: CRAC channel (Orai and STIM) expression, splicing and posttranslational modifiers. Niemeyer BA. Am J Physiol Cell Physiol. 2016 Feb 24:ajpcell.00034.2016. doi: 10.1152/ajpcell.00034.2016.

The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses. Wahl S, Magupalli VG, Dembla M, Katiyar R, Schwarz K, Köblitz L, Alpadi K, Krause E, Rettig J, Sung CH, Goldberg AF, Schmitz F. J Neurosci. 2016 Feb 24;36(8):2473-93. doi: 10.1523/JNEUROSCI.2275-15.2016.

Components and Mechanisms of Import, Modification, Folding, and Assembly of Immunoglobulins in the Endoplasmic Reticulum. Zimmermann R. J Clin Immunol. 2016 Feb 29. doi: 10.1007/s10875-016-0250-0.

Januar

Adenosine A1 receptor activation attenuates cardiac hypertrophy and fibrosis in response to α1 -adrenoceptor stimulation in vivo. Puhl SL, Kazakov A, Müller A, Fries P, Wagner DR, Böhm M, Maack C, Devaux Y. Br J Pharmacol. 2016 Jan;173(1):88-102. doi: 10.1111/bph.13339.

Regulation of Ca2+ signaling in prostate cancer cells. Kilch T, Kappel S, Peinelt C. Channels (Austin). 2016 Jan 8:1-2.

Podoplanin discriminates distinct stromal cell populations and a novel progenitor subset in the liver. Eckert C, Kim YO, Julich H, Heier EC, Klein N, Krause E, Tschernig T, Kornek M, Lammert F, Schuppan D, Lukacs-Kornek V. Am J Physiol Gastrointest Liver Physiol. 2016 Jan 1;310(1):G1-G12. doi: 10.1152/ajpgi.00344.2015.

Andere

Chemosensory Transduction. The Detection of Odors, Tastes, and Other Chemostimuli. 1st Edition. Zufall F, Munger S. Academic Press. 18 Feb 2016.