Ca2+-Signale:
Molekulare Mechanismen und Integrative Funktionen
Sonder­forschungs­bereich 894

Publikationen 2015

Dezember

CRAC channels, calcium, and cancer in light of the driver and passenger concept. Hoth M. Biochim Biophys Acta. 2015 Dec 17. pii: S0167-4889(15)00430-9. doi: 10.1016/j.bbamcr.2015.12.009.

November

Pregnancy and estrogen enhance neural progenitor-cell proliferation in the vomeronasal sensory epithelium. Oboti L, Ibarra-Soria X, Pérez-Gómez A, Schmid A, Pyrski M, Paschek N, Kircher S, Logan DW, Leinders-Zufall T, Zufall F, Chamero P. BMC Biol. 2015 Nov 30;13:104. doi: 10.1186/s12915-015-0211-8.

Cre-Mediated Recombination in Tas2r131 Cells - A Unique Way to Explore Bitter Taste Receptor Function Inside and Outside of the Taste System. Voigt A, Hübner S, Döring L, Perlach N, Hermans-Borgmeyer I, Boehm U, Meyerhof W. Chem Senses. 2015 Nov;40(9):627-39. doi: 10.1093/chemse/bjv049.

Complexins: small but capable. Mohrmann R, Dhara M, Bruns DCell Mol Life Sci. 2015 Nov;72(22):4221-35. doi: 10.1007/s00018-015-1998-8.

Cholinergic chemosensory cells of the thymus medulla express the bitter receptor Tas2R131. Soultanova A, Voigt A, Chubanov V, Gudermann T, Meyerhof W, Boehm U, Kummer W. Int Immunopharmacol. 2015 Nov;29(1):143-7. doi: 10.1016/j.intimp.2015.06.005.

Identification of cholinergic chemosensory cells in mouse tracheal and laryngeal glandular ducts. Krasteva-Christ G, Soultanova A, Schütz B, Papadakis T, Weiss C, Deckmann K, Chubanov V, Gudermann T, Voigt A, Meyerhof W, Boehm U, Weihe E, Kummer W. Int Immunopharmacol. 2015 Nov;29(1):158-65. doi: 10.1016/j.intimp.2015.05.028.

Interactions with membrane lipids and SNARE complex underlie dual roles for Calcium-dependent activator proteins for secretion (CAPS) in large dense-core vesicles (LDCVS) priming. Stevens DR, Ratai O, Rettig J. Physiological Mini Reviews, Vol.8 Nº6, 2015.

Oktober

Transient receptor potential melastatin 4 channel contributes to migration of androgen-insensitive prostate cancer cells. Holzmann C, Kappel S, Kilch T, Jochum MM, Urban SK, Jung V, Stöckle M, Rother K, Greiner M, Peinelt COncotarget. 2015 Oct 19. doi: 10.18632/oncotarget.6157.

Differential Redox Regulation of Ca(2+) Signaling and Viability in Normal and Malignant Prostate CellsHolzmann C, Kilch T, Kappel S, Dörr K, Jung V, Stöckle M, Bogeski I, Peinelt CBiophys J. 2015 Oct 6;109(7):1410-9. doi: 10.1016/j.bpj.2015.08.006.

Essential roles for Cavβ2 and Cav1 channels in thymocyte development and T cell homeostasis. Jha A, Singh AK, Weissgerber P, Freichel M, Flockerzi V, Flavell RA4, Jha MK. Sci Signal. 2015 Oct 20;8(399):ra103. doi: 10.1126/scisignal.aac7538.

September

Structure of the native Sec61 protein-conducting channel. Pfeffer S, Burbaum L, Unverdorben P, Pech M, Chen Y, Zimmermann R, Beckmann R, Förster F. Nat Commun. 2015 Sep 28;6:8403. doi: 10.1038/ncomms9403.

Gene Targeting in Neuroendocrinology. Candlish M, de Angelis R, Götz V, Boehm U. Compr Physiol. 2015 Sep 20;5(4):1645-76. doi: 10.1002/cphy.c140079.

Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure. Nickel AG, von Hardenberg A, Hohl M, Löffler JR, Kohlhaas M, Becker J, Reil JC, Kazakov A, Bonnekoh J, Stadelmaier M, Puhl SL, Wagner M, Bogeski I, Cortassa S, Kappl R, Pasieka B, Lafontaine M, Lancaster CR, Blacker TS, Hall AR, Duchen MR, Kästner L, Lipp P, Zeller T, Müller C, Knopp A, Laufs U, Böhm M, Hoth MMaack CCell Metan. 2015 Sep 1;22(3):472-84. doi: 10.1016/j.cmet.2015.07.008.

In Utero Development of Kisspeptin/GnRH Neural Circuitry in Male Mice. Kumar D, Periasamy V, Freese M, Voigt A, Boehm UEndocrinology. 2015 Sep;156(9):3084-90. doi: 10.1210/EN.2015-1412.

Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism-pathogenesis, diagnosis and treatment. Boehm U, Bouloux PM, Dattani MT, de Roux N, Dodé C, Dunkel L, Dwyer AA, Giacobini P, Hardelin JP, Juul A, Maghnie M, Pitteloud N, Prevot V, Raivio T, Tena-Sempere M, Quinton R, Young J. Nat Rev Endocrinol. 2015 Sep;11(9):547-64. doi: 10.1038/nrendo.2015.112.

RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors. Grabner CP, Gandini MA, Rehak R, Le Y, Zamponi GW, Schmitz F. J Neurosci. 2015 Sep 23;35(38):13133-47. doi: 10.1523/JNEUROSCI.0658-15.2015.

 

August

Cell-type-specific tuning of Cav1.3 Ca(2+)-channels by a C-terminal automodulatory domain. Scharinger A, Eckrich S, Vandael DH, Schönig K, Koschak A, Hecker D, Kaur G, Lee A, Sah A, Bartsch D, Benedetti B, Lieb A, Schick B, Singewald N, Sinnegger-Brauns MJ, Carbone E, Engel J, Striessnig J. Front Cell Neurosci. 2015 Aug 24;9:309. doi: 10.3389/fncel.2015.00309.

Hypothalamic gonadotropin-releasing hormone (GnRH) receptor neurons fire in synchrony with the female reproductive cycle. Schauer C, Tong T, Petitjean H, Blum T, Peron S, Mai O, Schmitz FBoehm ULeinders-Zufall TJ Neurophysiol. 2015 Aug;114(2):1008-21. doi: 10.1152/jn.00357.2015.

Behavior and Properties of Mature Lytic Granules at the Immunological Synapse of Human Cytotoxic T Lymphocytes. Ming M, Schirra C, Becherer U, Stevens DR, Rettig J. PLoS One. 2015 Aug 21;10(8):e0135994. doi: 10.1371/journal.pone.0135994.

Genetic control of astrocyte function in neural circuits. Jahn HM, Scheller A, Kirchhoff F. Front Cell Neurosci. 2015 Aug 17;9:310. doi: 10.3389/fncel.2015.00310.

Juli

VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity. Marshall MR, Pattu V, Halimani M, Maier-Peuschel M, Müller ML, Becherer U, Hong W, Hoth M, Tschernig T, Bryceson YT, Rettig J. J Cell Biol. 2015 Jul 6;210(1):135-51. doi: 10.1083/jcb.201411093.

Transsynaptic tracing from taste receptor cells reveals local taste receptor gene expression in gustatory ganglia and brain. Voigt A, Bojahr J, Narukawa M, Hübner S, Boehm U, Meyerhof W. J Neurosci. 2015 Jul 1;35(26):9717-29. doi: 10.1523/JNEUROSCI.0381-15.2015.

Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidaseBode M, Woellhaf MW, Bohnert M, Laan Mv, Sommer F, Jung MZimmermann R, Schroda M, Herrmann JM. Mol Biol Cell. 2015 Jul 1;26(13):2385-401. doi: 10.1091/mbc.E14-11-1526.

A Binary Genetic Approach to Characterize TRPM5 Cells in Mice. Kusumakshi S, Voigt A, Hübner S, Hermans-Borgmeyer I, Ortalli A, Pyrski M, Dörr J, Zufall FFlockerzi V, Meyerhof W, Montmayeur JP, Boehm UChem Senses. 2015 Jul;40(6):413-25. doi: 10.1093/chemse/bjv023.

Facilitation of Orai3 targeting and store-operated function by Orai1. Alansary D, Bogeski I, Niemeyer BABiochim Biophys Acta. 2015 Jul;1853(7):1541-50. doi: 10.1016/j.bbamcr.2015.03.007.

Conditional Viral Tract Tracing Delineates the Projections of the Distinct Kisspeptin Neuron Populations to Gonadotropin-Releasing Hormone (GnRH) Neurons in the Mouse. Yip SH, Boehm U, Herbison AE, Campbell RE. Endocrinology. 2015 Jul;156(7):2582-94. doi: 10.1210/en.2015-1131.

Co-chaperone specificity in gating of the polypeptide conducting channel in the membrane of the human endoplamic reticulum. Schorr S, Klein, MC, Gamayun I, Melnyk A, Jung M, Schäuble N, Wang Q, Hemmis B, Bochen F, Greiner M, Lampel P, Urban SK, Haßdenteufel S, Dudek J, Chen XZ, Wagner R, Cavalié AZimmermann R. J Biol Chem. 2015 Jul 24;290(30):18621-35. doi: 10.1074/jbc.M115.636639.

Exercise attenuates inflammation and limits scar thinning after myocardial infarction in mice. Puhl SL, Müller A, Wagner M, Devaux Y, Böhm M, Wagner DR, Maack C. Am J Physiol Heart Circ Physiol. 2015 Jul 15;309(2):H345-59. doi: 10.1152/ajpheart.00683.2014. 

Mai

Innate Predator Odor Aversion Driven by Parallel Olfactory Subsystems that Converge in the Ventromedial Hypothalamus. Pérez-Gómez A, Bleymehl K, Stein B, Pyrski M, Birnbaumer L, Munger SD, Leinders-Zufall T, Zufall F, Chamero P. Curr Biol. 2015 May 18;25(10):1340-6. doi: 10.1016/j.cub.2015.03.026.

April

Estrogen permits vasopressin signaling in preoptic kisspeptin neurons in the female mouse. Piet R, Fraissenon A, Boehm U, Herbison AE. J Neurosci. 2015 Apr 29;35(17):6881-92. doi: 10.1523/JNEUROSCI.4587-14.2015.

A STIM2 splice variant negatively regulates store-operated calcium entry. Miederer AM, Alansary D, Schwär G, Lee PH, Jung M, Helms V, Niemeyer BANat Commun. 2015 Apr 21;6:6899. doi: 10.1038/ncomms7899.

Influence of the β2-Subunit of L-Type Voltage-Gated Cav Channels on the Structural and Functional Development of Photoreceptor Ribbon Synapses. Katiyar R, Weissgerber P, Roth E, Dörr J, Sothilingam V, Garcia Garrido M, Beck SC, Seeliger M, Beck ASchmitz FFlockerzi VInvest Ophthalmol Vis Sci. 2015 Apr;56(4):2312-24. doi: 10.1167/iovs.15-16654.

März

Increased water flux induced by an aquaporin-1/carbonic anhydrase II interaction. Vilas G, Krishnan D, Loganathan SK, Malhotra D, Liu L, Beggs MR, Gena P, Calamita G, Jung M, Zimmermann R, Tamma G, Casey JR, Alexander RT. Mol Biol Cell. 2015 Mar 15;26(6):1106-18. doi: 10.1091/mbc.E14-03-0812.

Positive, but not negative feedback actions of estradiol in adult female mice require estrogen receptor α in kisspeptin neurons. Dubois SL, Acosta-Martínez M, DeJoseph MR, Wolfe A, Radovick S, Boehm U, Urban JH, Levine JE. Endocrinology. 2015 Mar;156(3):1111-20. doi: 10.1210/en.2014-1851. 

Protein transport into the human endoplasmic reticulum. Dudek J, Pfeffer S, Lee PH, Jung M, Cavalié A, Helms V, Förster F, Zimmermann R. J Mol Biol. 2015 Mar 27;427(6PA):1159-1175. doi: 10.1016/j.jmb.2014.06.011.

Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens. Bufe B, Schumann T, Kappl R, Bogeski I, Kummerow C, Podgórska M, Smola S, Hoth MZufall FJ Biol Chem. 2015 Mar 20;290(12):7369-87. doi: 10.1074/jbc.M114.626747.

Januar

Specialized subpopulations of kisspeptin neurons communicate with GnRH neurons in female mice. Kumar D, Candlish M, Periasamy V, Avcu N, Mayer C, Boehm U. Endocrinology. 2015 Jan;156(1):32-8. doi: 10.1210/en.2014-1671.

TAS2R bitter taste receptors regulate thyroid function. Clark AA, Dotson CD, Elson AE, Voigt A, Boehm U, Meyerhof W, Steinle NI, Munger SD. FASEB J. 2015 Jan;29(1):164-72. doi: 10.1096/fj.14-262246.

β-catenin stabilization in gonadotropes impairs FSH synthesis in male mice in vivo. Boerboom D, Kumar V, Boyer A, Wang Y, Lambrot R, Zhou X, Rico C, Boehm U, Paquet M, Céleste C, Kimmins S, Bernard DJ. Endocrinology. 2015 Jan;156(1):323-33. doi: 10.1210/en.2014-1296.