Ca2+-Signale:
Molekulare Mechanismen und Integrative Funktionen
Sonder­forschungs­bereich 894

Publikationen 2011

Dezember

Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Ertürk A, Mauch CP, Hellal F, Förstner F, Keck T, Becker K, Jährling N, Steffens H, Richter M, Hübener M, Kramer E, Kirchhoff F, Dodt HU, Bradke F. Nat Med. 2011 Dec 25;18(1):166-71. doi: 10.1038/nm.2600. 

November

The synaptic ribbon is a site of phosphatidic acid generation in ribbon synapses. Schwarz K, Natarajan S, Kassas N, Vitale N, Schmitz FJ Neurosci. 2011 Nov 2;31(44):15996-6011. doi: 10.1523/JNEUROSCI.2965-11.2011.

Redox regulation of calcium ion channels: chemical and physiological aspects. Bogeski I, Kappl R, Kummerow C, Gulaboski R, Hoth MNiemeyer BACell Calcium. 2011 Nov;50(5):407-23. doi: 10.1016/j.ceca.2011.07.006.

Melanopsin signalling in mammalian iris and retina. Xue T, Do MT, Riccio A, Jiang Z, Hsieh J, Wang HC, Merbs SL, Welsbie DS, Yoshioka T, Weissgerber P, Stolz S, Flockerzi VFreichel M, Simon MI, Clapham DE, Yau KW. Nature. 2011 Nov 2;479(7371):67-73. doi: 10.1038/nature10567.

September

Newborn interneurons in the accessory olfactory bulb promote mate recognition in female mice. Oboti L, Schellino R, Giachino C, Chamero P, Pyrski M, Leinders-Zufall T, Zufall F, Fasolo A, Peretto P. Front Neurosci. 2011 Sep 28;5:113. doi: 10.3389/fnins.2011.00113.

ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance. Qu B, Al-Ansary D, Kummerow C, Hoth M, Schwarz EC. Cell Calcium. 2011 Sep;50(3):261-9. doi: 10.1016/j.ceca.2011.05.015.

Excitable T cells: Ca(v)1.4 channel contributions and controversies. Niemeyer BAHoth MImmunity. 2011 Sep 23;35(3):315-7. doi: 10.1016/j.immuni.2011.09.001

August

G protein G{alpha}o is essential for vomeronasal function and aggressive behavior in mice. Chamero P, Katsoulidou V, Hendrix P, Bufe B, Roberts R, Matsunami H, Abramowitz J, Birnbaumer L, Zufall FLeinders-Zufall TProc Natl Acad Sci USA. 2011 Aug 2;108(31):12898-903. doi: 10.1073/pnas.1107770108.

A monoclonal antibody for in vivo detection of peroxisome-associated PTS1 receptor. Cizmowski C, Jung M, Erdmann R, Schliebs W. Hybridoma (Larchmt). 2011 Aug;30(4):387-91. doi: 10.1089/hyb.2011.0038.

In Situ Visualization of Protein Interactions in Sensory Neurons: Glutamic Acid-Rich Proteins (GARPs) Play Differential Roles for Photoreceptor Outer Segment Scaffolding. Ritter LM, Khattree N, Tam B, Moritz OL, Schmitz F, Goldberg AF. J Neurosci. 2011 Aug 3;31(31):11231-43. doi: 10.1523/JNEUROSCI.2875-11.2011.

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation. Quintana A, Pasche M, Junker C, Al-Ansary D, Rieger H, Kummerow C, Nuñez L, Villalobos C, Meraner P, Becherer URettig JNiemeyer BAHoth MEMBO J. 2011 Aug 16;30(19):3895-912. doi: 10.1038/emboj.2011.289.

Juli

Calmodulin regulation of the calcium-leak channel Sec61 is unique to vertebrates. Harsman A, Kopp A, Wagner R, Zimmermann RJung MChannels (Austin). 2011 Jul-Aug;5(4):293-8.

Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytes. Pattu V, Qu B, Marshall M, Becherer U, Junker C, Matti U, Schwarz EC, Krause EHoth MRettig JTraffic. 2011 Jul;12(7):890-901. doi: 10.1111/j.1600-0854.2011.01193.x.

Sec62 protein level is crucial for the ER stress tolerance of prostate cancer. Greiner M, Kreutzer B, Lang S, Jung V, Cavalié A, Unteregger G, Zimmermann R, Wullich B. Prostate. 2011 Jul;71(10):1074-83. doi: 10.1002/pros.21324.

Live cell calcium imaging combined with siRNA mediated gene silencing identifies Ca²⁺ leak channels in the ER membrane and their regulatory mechanisms. Lang S, Schäuble N, Cavalié AZimmermann RJ Vis Exp. 2011 Jul 7;(53):e2730. doi: 10.3791/2730.

Juni

Docking of Lytic Granules at the Immunological Synapse in Human CTL Requires Vti1b-Dependent Pairing with CD3 Endosomes. Qu B, Pattu V, Junker C, Schwarz EC, Bhat SS, Kummerow C, Marshall M, Matti U, Neumann F, Pfreundschuh M, Becherer U, Rieger H, Rettig JHoth MJ Immunol. 2011 Jun 15;186(12):6894-904. doi: 10.4049/jimmunol.1003471. 

Calcium binding and transport by Coenzyme Q. Bogeski I, Gulaboski R, Kappl R, Mirceski VB, Stefova M, Petreska J, Hoth MJ Am Chem Soc. 2011 Jun 22;133(24):9293-303. doi: 10.1021/ja110190t.

Targeting Mitochondrial Oxidative Stress in Heart Failure Throttling the Afterburner. Maack C, Böhm M. J Am Coll Cardiol. 2011 Jun 28;58(1):83-6. doi: 10.1016/j.jacc.2011.01.032. 

A role for glia in the progression of Rett's syndrome. Lioy DT, Garg SK, Monaghan CE, Raber J, Foust KD, Kaspar BK, Hirrlinger PG, Kirchhoff F, Bissonnette JM, Ballas N, Mandel G. Nature. 2011 Jun 29;475(7357):497-500. doi: 10.1038/nature10214. 

Female reproductive maturation in the absence of kisspeptin/GPR54 signaling. Mayer C, Boehm UNat Neurosci. 2011 Jun;14(6):704-10. doi: 10.1038/nn.2818.

Mai

Sec61 complexes form ubiquitous ER Ca2+ leak channels. Lang S, Erdmann F, Jung M, Wagner R, Cavalié AZimmermann RChannels (Austin). 2011 May-Jun;5(3):228-35.

Male fertility depends on Ca2+ absorption by TRPV6 in epididymal epithelia. Weissgerber P, Kriebs U, Tsvilovskyy V, Olausson J, Kretz O, Stoerger C, Vennekens R, Wissenbach U, Middendorff R, Flockerzi VFreichel MSci Signal. 2011 May 3;4(171):ra27. doi: 10.1126/scisignal.2001791.

Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the CACNB2 gene. Meissner M, Weissgerber P, Camacho Londono JE, Prenen J, Link S, Ruppenthal S, Molkentin JD, Lipp P, Nilius B, Freichel MFlockerzi VJ Biol Chem. 2011 May 6;286(18):15875-82. doi: 10.1074/jbc.M111.227819.

TRPM3 is a nociceptor channel involved in the detection of noxious heat. Vriens J, Owsianik G, Hofmann T, Philipp SE, Stab J, Chen X, Benoit M, Xue F, Janssens A, Kerselaers S, Oberwinkler J, Vennekens R, Gudermann T, Nilius B, Voets T. Neuron. 2011 May 12;70(3):482-94. doi: 10.1016/j.neuron.2011.02.051.

April

Immune synapses: mitochondrial morphology matters. Junker C, Hoth MEMBO J. 2011 Apr 6;30(7):1187-9. doi: 10.1038/emboj.2011.72

Transient Receptor Potential Melastatin 1 (TRPM1) Is an Ion-conducting Plasma Membrane Channel Inhibited by Zinc Ions. Lambert S, Drews A, Rizun O, Wagner TF, Lis A, Mannebach S, Plant S, Portz M, Meissner M, Philipp SEOberwinkler JJ Biol Chem. 2011 Apr 8;286(14):12221-33. doi: 10.1074/jbc.M110.202945.

Transport of the Major Myelin Protein PLP is Directed by the R-SNAREs VAMP3 and VAMP7. Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, Krämer-Albers EM. J Neurosci. 2011 Apr 13;31(15):5659-72. doi: 10.1523/JNEUROSCI.6638-10.2011.

Loss-of-function mutations in sodium channel Na(v)1.7 cause anosmia. Weiss J, Pyrski M, Jacobi E, Bufe B, Willnecker V, Schick B, Zizzari P, Gossage SJ, Greer CA, Leinders-Zufall T, Woods CG, Wood JN, Zufall FNature. 2011 Apr 14;472(7342):186-90. doi: 10.1038/nature09975.

Genetic identification of GnRH receptor neurons: a new model for studying neural circuits underlying reproductive physiology in the mouse brain. Wen S, Götze IN, Mai O, Schauer C, Leinders-Zufall T, Boehm U. Endocrinology. 2011 Apr;152(4):1515-26. doi: 10.1210/en.2010-1208.

Interplay of defective excitation-contraction coupling, energy starvation, and oxidative stress in heart failure. Kohlhaas M, Maack CTrends Cardiovasc Med. 2011 Apr;21(3):69-73. doi: 10.1016/j.tcm.2012.03.002.

Februar

Vesicle pools: lessons from adrenal chromaffin cells. Stevens DR, Schirra C, Becherer U, Rettig JFront Synaptic Neurosci. 2011 Feb 1;3:2. doi: 10.3389/fnsyn.2011.00002.

Januar

Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum. Erdmann F, Schäuble N, Lang S, Jung M, Honigmann A, Ahmad M, Dudek J, Benedix J, Harsman A, Kopp A, Helms V, Cavalié A, Wagner R, Zimmermann REMBO J. 2011 Jan 5;30(1):17-31. doi: 10.1038/emboj.2010.284.

Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness. Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nürnberg P, Striessnig J, Bolz HJ. Nat Neurosci. 2011 Jan;14(1):77-84. doi: 10.1038/nn.2694.

Andere

Lessons of studying TRP channels with antibodies. In TRP channels, CRC methods in signal transduction series. Meissner M, Obmann VC, Hoschke M, Link S, Jung M, Held G, Philipp SEZimmermann RFlockerzi VM. X. Zhu, ed. 2011 CRC Press, New York, 135-148.

Strategies and Protocols to Generate Mouse Models with Targeted Mutations to Analyze TRP Channel Functions. Freichel M, Kriebs U, Vogt D, Mannebach S, Weissgerber P. In: Zhu MX, editor. SourceTRP Channels. Boca Raton (FL): CRC Press; 2011. Chapter 8.